pharm edaily

[Kim Saemi, Edaily Reporter] BioPlus Co., Ltd. on September 2 announced the launch of HUGRO, a new ingredient brand powered by growth factors, in September 2025. Introduced under the slogan ‘Beyond the Skin, a Cell-Awakening Booster,’ HUGRO aims to deliver next-generation skincare solutions based on biotechnology.

HUGRO (Source: BioPlus Co., Ltd.)

While growth factors promote cell generation and regeneration, they are easily degraded and, due to their large molecular size, face challenges in skin absorption and delivery. To overcome these limitations, BioPlus has applied its patented technologies: AUT (Anti-Ubiquitination Technology), which extends protein stability, and BMTS (Bio-Material Transdermal System Technology), which enhances skin barrier penetration. Through these innovations, the company has addressed key challenges associated with growth factor delivery and demonstrated significant effects in cell recovery.

BioPlus has developed a portfolio of 19 growth factors and plans to further expand its ingredient library and product lineup. This will be achieved through both single-factor and combination formulations tailored for a wide range of applications.

The first product will be an eyelash serum launched under the ‘HUGRO Topical Cell Booster’ series. Powered by HUGRO-H Complex, known for promoting hair growth, the serum is designed to stimulate follicle cells and promote fuller lashes by harnessing the regenerative role of growth factors in both skin and hair cells.

The first product will be an eyelash serum launched as part of the “Hugro Topical Cell Booster” series. Powered by Hugro-H Complex, known for promoting hair growth, the serum is designed to stimulate follicle cells and promote fuller lashes by harnessing the regenerative role of growth factors in both skin and hair cells.

With the launch of HUGRO, BioPlus aims to establish a differentiated position in the highly competitive cosmeceuticals market. The company stated, “Brands that combine growth factors with advanced technologies remain rare in both domestic and global skincare markets. By gradually expanding the HUGRO® lineup, we intend to enhance brand recognition and expand market presence.”

Meanwhile, BioPlus―established in 2003 as a specialist in hyaluronic acid fillers―has steadily expanded its presence in both domestic and global markets. Following the launch of its new brand HUGRO, the company is accelerating the development of its biopharmaceutical pipeline, which includes botulinum toxin and therapeutic candidates for obesity and diabetes.